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Updated: Aug 17, 2026

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American Society of Microbiology ABMM Exam Overview:

Certification Vendor:American Society for Microbiology (ASM) - American College of Microbiology
Exam Name:ABMM Certification Examination (American Board of Medical Microbiology)
Exam Number:ABMM
Exam Format:Written Examination, Oral Examination (may be required depending on candidate pathway), Credential/Document Review
Available Languages:English
Related Certifications:American Board of Medical Laboratory Immunology (ABMLI)
Sample Questions:American Society of Microbiology ABMM Sample Questions
Exam Way:In-person examination (location varies; administered under ASM certification program policies).
Pre Condition:Doctoral degree (PhD, MD, or equivalent) in microbiology or a related biomedical field, plus relevant clinical microbiology training/experience.

American Society of Microbiology ABMM Exam Syllabus Topics:

SectionObjectives
Topic 1: Laboratory Management & Quality Systems- Quality assurance and quality control
  • 1. Proficiency testing and validation
    • 2. Laboratory quality systems design
      - Regulatory compliance
      • 1. Clinical laboratory regulations and accreditation standards
        • 2. Safety and biosafety requirements
          Topic 2: Laboratory Operations- Instrumentation and methodologies
          • 1. Molecular diagnostic techniques
            • 2. Automated microbiology systems
              - Diagnostic workflow
              • 1. Test selection and interpretation
                • 2. Specimen handling and processing
                  Topic 3: Clinical Microbiology- Virology
                  • 1. Clinical viral pathogens
                    • 2. Diagnostic virology methods
                      - Mycology
                      • 1. Medical fungal infections
                        • 2. Laboratory identification of fungi
                          - Bacteriology
                          • 1. Antimicrobial susceptibility testing principles
                            • 2. Identification and classification of bacterial pathogens
                              - Parasitology
                              • 1. Human parasitic infections
                                • 2. Diagnostic techniques in parasitology
                                  Topic 4: Infectious Disease Principles- Pathogenesis
                                  • 1. Mechanisms of microbial infection
                                    • 2. Host-pathogen interactions
                                      - Epidemiology
                                      • 1. Transmission and outbreak investigation
                                        • 2. Public health microbiology

                                          American Society of Microbiology ABMM Sample Questions:

                                          1. A patient develops a severe skin infection after a puncture wound sustained while gardening. Culture of the wound exudate grows a Gram-positive, spore-forming bacillus that is anaerobic and produces a potent neurotoxin causing sustained muscle contraction. The MOST likely organism is:

                                          A) Clostridium botulinum
                                          B) Clostridium tetani
                                          C) Bacillus anthracis
                                          D) Clostridium perfringens


                                          2. A patient with a history of recurrent sinopulmonary infections and bronchiectasis is diagnosed with primary ciliary dyskinesia. Sputum cultures are most likely to persistently grow which of the following organisms?

                                          A) Haemophilus influenzae
                                          B) Pseudomonas aeruginosa
                                          C) Streptococcus pneumoniae
                                          D) Moraxella catarrhalis


                                          3. According to the current CDC-recommended laboratory algorithm for diagnosing HIV infection in adults and children aged >18 months, what is the recommended initial screening test?

                                          A) HIV-1/HIV-2 antibody differentiation immunoassay
                                          B) HIV RNA nucleic acid test (NAT)
                                          C) HIV-1/HIV-2 antigen/antibody combination immunoassay
                                          D) HIV-1 p24 antigen assay only


                                          4. A research laboratory is developing a novel diagnostic assay for early detection of sepsis. They are investigating the use of host biomarkers that are rapidly upregulated in response to bacterial infection. Which of the following biomarkers has shown promise for differentiating between systemic inflammatory response syndrome (SIRS) and sepsis?

                                          A) Interleukin-6 (IL-6)
                                          B) Erythrocyte sedimentation rate (ESR)
                                          C) C-reactive protein (CRP)
                                          D) Procalcitonin (PCT)


                                          5. A microbiology laboratory receives a blood culture from a patient with suspected bacterial endocarditis. After
                                          24 hours of incubation, Gram-positive cocci in clusters are observed on the Gram stain. Catalase test is positive, and coagulase test is negative. Further testing reveals susceptibility to novobiocin. The MOST likely organism is:

                                          A) Staphylococcus saprophyticus
                                          B) Staphylococcus aureus
                                          C) Staphylococcus lugdunensis
                                          D) Staphylococcus epidermidis


                                          Solutions:

                                          Question # 1
                                          Answer: B
                                          Question # 2
                                          Answer: A
                                          Question # 3
                                          Answer: C
                                          Question # 4
                                          Answer: D
                                          Question # 5
                                          Answer: D

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