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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

1. A microbiology laboratory receives a sample of cerebrospinal fluid from a patient with suspected bacterial meningitis. The Gram stain shows Gram-positive diplococci. Culture on blood agar shows alpha-hemolytic colonies that are bile soluble and optochin-sensitive. The MOST likely organism is:

A) Streptococcus pneumoniae
B) Listeria monocytogenes
C) Enterococcus faecalis
D) Streptococcus agalactiae

2. A patient with a history of chronic sinusitis develops a severe invasive fungal infection involving the nasal sinuses and extending into the orbit. Tissue biopsy reveals broad, aseptate hyphae with irregular branching.
The patient is diabetic and acidotic. The MOST likely causative organism belongs to the genus:

A) Fusarium
B) Scedosporium
C) Aspergillus
D) Mucor or Rhizopus

3. A patient with a history of travel to Southeast Asia presents with fever, severe headache, and altered mental status. CSF analysis reveals lymphocytic pleocytosis and elevated protein, but routine bacterial and viral cultures are negative. Serological testing of CSF is positive for IgM antibodies against Japanese encephalitis virus. The MOST likely mode of transmission for this infection is:

A) Ingestion of contaminated food or water.
B) Direct contact with infected animals.
C) Bite of an infected mosquito.
D) Respiratory droplets from an infected individual.

4. A microbiology laboratory is processing a throat swab for the detection of Group A Streptococcus. Culture on sheep blood agar reveals beta-hemolytic colonies. Which of the following tests can be used to presumptively identify Streptococcus pyogenes?

A) Coagulase test
B) Bile esculin hydrolysis
C) Catalase test
D) Bacitracin susceptibility

5. A researcher is studying the genetic relatedness of different isolates of Mycobacterium tuberculosis. Which of the following molecular typing methods provides the highest discriminatory power for distinguishing between closely related strains?

A) Whole-genome sequencing (WGS)
B) Spoligotyping
C) Pulsed-field gel electrophoresis (PFGE)
D) Restriction fragment length polymorphism (RFLP) analysis

Solutions: